Abstract

Recerıtly, malondialdehyde(MDA) has emerged as a marker and mid- product of lipid peroxidation caused by free oxygen radicals. In order to investigate the peroxidation damage of thrombolytic therapy, we seperated fifty patients who had had acute myocard infarction infarction into two different groups. The first one consisted of the patients who had received thrombolytic therapy and the second the patiens who not. We took their serums for MDA measurements at 0.,2.,6.,24. hours. And then we had followed up the patients in wiew of prognosis, left ventricular measurements, wall motions and diastolic function parameters by Doppler echocardiogram. Finally we compared the results between two groups. But the MDA levels in patients from patients who had received thrombolytic therapy had been higher at 2. and 6. hours.(p: 0.01 and p: 0.02) However we could not find any statistically significant difference between the two groups, in view of prognosis, lenf ventricular measurements, wall motions and diastolic function parameters.