Abstract

INTRODUCTION

We aim to investigate patients who hospitalized between January and June 2014 in our clinic and detected thrombocytopenia which it had during hospitalization or developing in follow-up in terms of thrombocytopenia of etiology, pathophysiology and need for platelet replacement therapy.

METHODS

A hundred and seventy-two patients who hospitalized between January and June 2014 in Tepecik Training and Research Hospital Clinic of Internal Medicine enrolled in study. Patients retrospectively investigated in terms of thrombocytopenia of etiology, pathophysiology and given platelet replacement therapy.

RESULTS

: Eighty-two women and 90 men were of 172 patients. The mean age of the patients was 61. Average hospitalized platelet value was 78 800 / L and discharged value was 104 100 / L. Thrombocytopenia depending on the solid organ malignancies was detected as the most frequent cause. There was platelet destruction in 60 patients and bone marrow suppression in 112 patients. Cause of depending on the platelet destruction had occured younger age according bone marrow suppression related causes. Apheresis platelet transfusion had given for 27 patients and had used an average of 1.8 units. Random platelet transfusion how derived whole blood had given for 38 patients and had used an average of 19.7 units. When compared output platelet count and the number of these patients died, no significant difference between giving platelets from whole blood and apheresis platelets were determined.

DISCUSSION AND CONCLUSION

The etiology should be clarified at a patient who determined thrombocytopenia. The diagnosis can be accessed more easily with classification as pathophysiological. Platelet transfusions should be performed when it need. There was a need more prospective studies with larger groups of patients about the approach to patients with thrombocytopenia.